Ralph, I have Sayle ancestors in Andreas, who married (several times!) Radcliffe and Teare - three of the most common names there. They were a real headache trying to trace correctly.
But it is possible, with wills probably being the best source for the really common names in an area.
See this thread: http://www.isle-of-man.com/cgi-bin/interests/genealogy/bulletin/index.pl?noframes;read=12095
If you are able to work out your ones past Peel to Andreas, I have gathered a lot of Andreas Sayle records over the years.
Sue