Adrienne--thanks to you for providing additional info on this Caine line and clearing up the parentage of Margaret Caine Quiggin Knickle Quayle. If you discover more on Hugh Caine/Ann Moore, I am interested.
I'll also look to flesh out the lines you've already mentioned as I'm interested in all the surnames, especially the Caines & Quayles.
Genealogy does indeed "take a village".
Donna