I think that Margaret Caine ch 3 Sep 1688 Michael was d/o John Caine milner Ballacurleod Michael & Ann Corlett (md 1685 Ballaugh)
Her first husband was Patrick Quiggin ch 22 Apr 1686 Michael s/o Jon Quiggin and Elinor McBooy (md 1669)
Patrick Quiggin & Margaret Caine were md 7 Jul 1719 Michael
They had 5 children
1. Margt 30 May 1720 KM
2. Joney 19 Apr 1722 KM buried 1 Sep 1725 KM died from small pox p 107
KM bur reg
3. Christin 26 Jan 1725 KM could have married Daniel Garret 10 Aug 1754
Onchan
4. Jony (Joaney on IGI mg record) 11 Oct 1728 KM md 14 Dec 1754 Kirk
German John Caine of Ballagirr.
5. Jon 6 Jun 1731 KM md Mary Gell 15 Dec 1765

Patrick Quiggin died 24 Jan 1732 summary will on Manx Note Book full will seems to have fallen off the list, I have it

Margaret Caine Quiggin then md #2 William Knickle/Nichol 15 Apr 1733 KM
They had 2 children
1 Hugh 11 Jan 1736
2 Mary 17 Oct 1742

William Knickle/Nichol was bur 11 Jul 1743 KM
His summary will is on Manx Note Book

I don't have anything re her marrying John Quayle Ballahonnay Michael and would be interested in those details.

Donna