I have Margaret Crowe as Robert Cain II's 2nd wife and his 1st wife and family as:

.1 Robert CAIN c.05 Jun 1774 Braddan m.07 May 1803 Braddan bur.30 Jan 1849 St Lukes Baldwin
.1+ Jane (Kissack) CAIN b.1776 (or 1781) Rushen
..2 Robert CAIN II c.13 Jan 1804 Braddan
..2+ Elizabeth (Quiggin) CAIN b.02 Jul 1803 Braddan d.15 May 1849 Douglas m.13 Sep 1828 Braddan
...3 William James CAIN c.30 Nov 1828 Braddan
...3 John CAIN c.10 Oct 1830 Douglas St George
...3 Henry CAIN c.22 Apr 1833 Douglas St George
...3 Elizabeth CAIN c.18 Mar 1835 (twin) Douglas St George
...3 Thomas CAIN c.18 Mar 1835 (twin) Douglas St George
...3 Jane CAIN c.05 Nov 1837 Douglas St George
...3 Christian CAIN c.09 Jan 1840 Douglas St Barnabas
...3 Anna CAIN c.20 Feb 1842 Douglas St Mathews
...3 Joseph CAIN c.02 Nov 1845 Douglas St Mathews
..2++ Margaret (Crowe) CAIN m.12 Nov 1853 Braddan