Thanks Frances I think we have a good idea which was Eleanor Killip's china shop now - underneath Boot's toothpaste counter!
I will try to look at the 25" plan in the museum during my next visit.
Perhaps you can help with her husband's business - he was a shoemaker in Duke Street in 1823 (Pigot's Directory), but we have no idea where - can you think of any source of information that might help to identify which property (probably buried underneath Victoria Street!) - rental books or similar?