does the following ring any bells
Thomas Quilliam + Margt Ronan m Malew 1806 - subsequent fam in Santan but 2nd child Thomas bapt Malew 1809 tho always states born Santan ;
Thomas + Ann Kneale m Oct 1840 at Braddan tho think they are living appart in 1841 - by 1851 in Hanover Street Douglas Thomas a labourer - son John born in Douglas abt 1854 married Sophia Cannell (he was a french polisher living in multi-occupant 1 Gt Nelson St in 1881 with son Silvester born in Dec 1879.

You can check out much at www,imuseum.im and if it all matches trace back Thomas