John Killey + mary callow is where I think we started - btw ruth is given as c/o John Killey + cath callow (no marriage found)
the catch is that his stated age at each opportunity does not agree.

Marriage in Patrick would suggest Mary is of that parish - you should borrow the mormon parish film and check this marriage - it should indicate if she was a widow for example(the IGI doesn't always manage to include this minor fact!) as callow is extremely unusual in Patrick - the witnesses might also help

Their first daughter Margaret I think married John Quilliam - Patrick 18340524 - by 1851 found in douglas; I could find Ruth in Jurby in 1841 as a servant but no marriage/burial/appearance in 1851 (ruth is extremely uncommon manx name)