Have you considered a possibility that Samuel Brew may have gone across to England and died while there?
A Samuel Brew's death is recorded for the March quarter of 1865 in North Derby, Liverpool at www.freebmd.rootsweb.com Unfortunately no age is given. References are Vol 8b, page 480.
I hope this is not a red herring for you, but may be worth checking as there were many Manx/ex-Manx in Liverpool and especially in the N Derby/West Derby area.
Elizabeth