Hi Colin,
Re. "Anyone any ideas where or how I can find the wedding to a Clarke.." I think you need to first find out all you can from known existing records, such as the details on her marriage cert which Mary M found, if you don't already have this:
Year Surname, Name, Parish/Town, Where Married, Page, Entry, Register
1916 Clarke, Frances Marion Christian, Peel, Peel, 268 COE
1916 Quayle, Philip Henry, Greenock, Peel, 268 COE
[No Entry number given in ManxBMD.com]
You can buy the cert from the Registry: www.gov.im/registries/general/civilregistry/ (see "Contacts" at the top, if you are not in the IOM).
Then, if you post the details on this board, someone may be able to help further.
Sue