WOW! Too many John Kermeens, that's for sure!
We'll have to dig more to figure out which 1801-2 Johns fit where.

As for Mary Caine I have a candidate
It appears that Mary Caine Kermeen married #2 John Sayle 13 JUL 1865 Andreas

1871 Index
Andreas 4 19
Sayle
John 39 b Andreas
Mary 34 b Andreas
John 5 b Andreas
George 3 b Andreas
Martha 2 b Andreas
Mary A Kermeen 11

1881 Andreas
03,05,023,SAYLE, John,B'Cross,Head,Married,50,Farmer 28 Acs,Andreas,Andreas
03,05,023,SAYLE, Mary,B'Cross,Wife,Married,45,Farmers Wife,Lezayre,Andreas
03,05,023,SAYLE, George,B'Cross,Son,,11,Farmers Son,Andreas,Andreas
03,05,023,SAYLE, Horatio,B'Cross,Son,,4,,Andreas,Andreas

Mary Margaret CAINE ch 12 Mar 1834 Lezayre d/o Philip CAINE and Ann COTTIER

If this is the right family, I have come full circle.
These are the ancestors of Carolyn Caine who started me in IOM research many yrs ago.
Also if the right family, I have lots of info on the Caines and Cottiers.

You have done a great deal of work, Sue! Thanks so much for all the info.
Perhaps we'll figure out all of these darn Johns.

Donna