Anthony McGuffog married Alice Farrimond on 30th August 1812 at Farnworth, Prescot, Lancashire.
The couple had eight known children (so far):
William McGuffie born 13th May 1813 at Wigan, Lancs and was christened on 16th May 1813 at St. Pauls, Standishgate, Wigan;
James McGuffie born 7th July 1814 at Wigan, Lancs and was christened on 28th July 1814 at St. Pauls, Standishgate, Wigan. He died on 11th September 1902 at Ash Springs, Lincoln, Nevada USA;
Anthony McGuffie born on 1st March 1816 at Wigan Lancs and was christened on 31st March 1816 at St Pauls, Standishgate, Wigan;
Susannah McGuffie born 7th February 1818 at Wigan, Lancs and was christened on 22nd March 1818 at St Pauls, Standishgate, Wigan;
Martin McGuffie born 24th October 1830 and christened on 22nd February 1831 at Bold Street Universalist, Liverpool, Lancs;
George McGuffie born 21st January 1834 and christened at Bold Street Universalist, Liverpool, Lancs;
Alice McGuffog born 28th August 1836 and christened 10th October 1836 at Bold Street Universalist, Liverpool, Lancs. She died on 30th April 1902.
Alexander McGuffog born 1839 at Stanton Isle of Man and was christened on 30th September 1839 at Stanton Isle of Man.

Alexander McGuffog married Christiannah Snaylam at St Albans, Liverpool, Lancs in (June quarter) 1868. Christiannah was born in Chorley, Lancs in 1845.

The couple had two known children (so far):

Edith Alice McGuffog born in the March quarter of 1871 at Liverpool, Lancs;
Hannah Florence McGuffog born in the June quarter of 1878 at Liverpool, Lancs.

I have been on the FreeBMD site and found that a Thomas Anthony A McGuffog died aged 0 in the September quarter of 1873. It seems he had been born in the June quarter of 1873.