Brian - I'll be interested to know which of John & Elizabeth's lines you belong to. I guess you must belong to Matthew's progeny. I have a good deal of info. on them from the history deposited at the San Diego Historical Soc. [Your cousin Emily Kelly Switters was a President Emeritus of the SDHS].
For John & Elizabeth's ancestry, there is very extensive coverage in the LDS website: go to www.familysearch and search on Elizabeth Quine, born Isle of Man 1797, daughter of John Quine, married John Kelly.
For the Quines, look at my website www.manxroots.com + follow Quine.
My e-mail address appears on the Quine page. Could you forward details of your descent?