while asking on a irish site about finding out if catherine cain went to ireland after 1922,
this one reply [ they are very good this site i found because they enquire,
------------------------------
John Isaac Nelson Caine and Margaret Brew had the following children

James Caine born 1885 Booille Vane Farm East, Baldwin, Idle of Man
married Eleanor Christian 29th May 1910 Isle Of Man

William C Caine born 1887 Isle Of Man

Samuel Mark Caine born 1880 Booille Vane Farm East
Christened at St Lukes Church Isle of Man

John Nelsaon Caine born 1883 Booille
died 31st May 1884
buried at St Lukes

Mark Caine born 1890 Isle Of Man
died 31st January 1910 Harrissmith, Orange Free State, South Africa

Catherine Annie born 1894 Booille, died 26th July 1901 buried St Lukes

Now this Catherine would have only been 7 years old, but they may have had another daughter after her birth which was a custom to name another child after one who died

Could they have had a nother child and i hope im not treading on any ones toes here as im only wondering,