Hello Raymond,
The Mark Christian & Margaret Kissack marriage 19 Nov.1814 in Maughold has no other identifying details on it, so doesn't say that she is from Lezayre.
The IGI has another Mark Christian marriage to a Margaret Christian 18 Oct.1791 Bride.
Are you certain which of these two Mark Christian and wife Margaret you are looking for? Names and dates of child /children?

The Maughold ones had children baptised from 1817 to 1837. Maughold Mark Christian was buried aged 69, Pt y vullin, 21 Feb 1854.
Mark son of William Christian & Ann Kelly bapt Parish Church 9 Jan 1785.

In the 1851 census the family is in Lewaigue, Maughold (under "Mack" Christian in Ancestry index) with Mark giving his age as 68 b.Maughold and wife Margaret 58 b.Lezayre, with daur Cathrine 23 and son Mark 13 both b.Maughold. In 1861 at Cottage on Lewaigue, Maughold, Margt Christian, widow, gives her age as 76 b.Lezayre, daur Cath unm., 27, b. Maughold, and Robt Corkill Grandson aged 1 b.Maughold. - So the ages are pretty inconsistent.
Margaret CHRISTIAN aged 78, Lewaigue, buried Maughold Sep 23 1870.

The Maughold one was Margaret Kissack of Lezayre, judging by the census entries, with a widely varying age. If correct at burial b.c.1792 there are two possible bapts in Lezayre for her [IGI].

Sue