I will contact you by email.  I have quite a bit of info on the Caine line--Betty Rose von Osten of Belfair, Washington USA descends from this line.  Ann was Mathias' first wife; after she died he married Catherine Ann Craine in 1834.  Betty descends from John of the second marriage.  Brian Lawson has info on the Lawson family so you may be in business .
I am excited about the possiblity of finding new info and new connections.  I shall be eager to hear about your connection to this line.
Donna in Gig Harbor, WA