Probably not much help to your specific question, but I am descended from Isabel Key.
It seems that the names Key, Kay, Kaye and Quay etc were one and the same.....
However Isabel Key born abt 1756 married a John Fick in Kirk German (Peel) 1785 - unfortunately for me there were 2 possible Isabels that I couldn't separate, so my line 'stops' there - but there were many Keys in Kirk German.
There is a Bill Kaye who is a member of the IOMFHS - we were briefly in contact a few months ago - it might be worth contacting him.