I've found some bits and pieces.
From Brian's indexes. Looks like there is a daughter Elizabeth Eleanor b a yr? after Henry Q
1901 Census Index
Piece 5302 Fol 153 Scd 85
Henry Q Wade 20
Elizabeth E Wade 42
Elizabeth E 19

1891 Census Index
Douglas 12 125
Henry Q Wade 10 b Ramsey
Elizabeth E 62 b Douglas
Elizabeth E 9 b Ramsey

James Henry died in Dec 1881 age 31
Maughold MI
ZD29
In affectionate remembrance of James Henry Wade of Ramsey, Chemist who departed this life December 28th 1881 aged 31 years
Twas hard to part with one we loved
But Jesus called her (him?)home
from this wide world of grief and pain
to rest upon his throne

Age is wrong but this is probably Elizabeth Eleanor Qualtrough Wade?
Braddan MI
Section One
Block Three
#1615
In memory of William Frederick son of William and ......
died....
aged 4 year...
Affectionate Remembrance of William Qualtrough ship builder of Douglas who died 3rd January 1878 aged 53 years
In affectionate remembrance of Eleanor wife of William Qualtrough who died 12th March 1918 aged 87 years
also Elizabeth Eleanor wife of George Henry Wade and daughter of William and Eleanor Qualtrough who died 24th March 1918 aged 39 years

Footstone George H Middleton who died January 16th 1864 aged 64 years

Maughold Monumental Inscriptions
Old Yard
ZD30
In memorium Elizabeth wife of John Wade of Ramsey who died May 14th 1871 aged 65 years
John Wade born 28 Sep 1801 died 12 Nov 1899
John Wade and Elizabeth Lace
John is s/o James Wade & Mary Christian
I wonder if Elizabeth is d/o Patrick Lace & Judith Karran of German?