Found this posting on the NAMA BB which seems likely to be very relavant to your research Melany.....

James Quine

Posted By: Carol Hoopingarner
Date: Thursday, 10 May 2001, at 10:36 p.m.

I am looking for information of James Quine who e, emigrated to America in 1784 with his wife, Jane and 2 children, James Jr, born 1823 and Jane. The left from Doulas, Isle of Man. They had 4 more children in America, Henry, Mary, John and Thomas. Thomas was my ancester, born in Ohio of Mr. 6, 1835. Need info prior to emigration, can share info after

Hope you can make contact with Carol
Good luck.
Elizabeth